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Wysłany: Śro 20:48, 25 Kwi 2007
Temat postu: Trodazone information
Do not take more or less of it, take it more often, or take it for a longer time than prescribed by your doctor
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Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides
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Drinking grapefruit juice is discouraged in patients taking trazodone
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While trazodone is not a true member of the SSRI class of antidepressants, it does still share many properties of the SSRIs, especially the possibility of discontinuation syndrome if the medication is stopped too quickly
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Anorexia and anxiety were reported significantly more often for the bupropion treatment group, whereas somnolence, appetite increase, and edema were reported signi
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Continue to take trazodone even if you feel well
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Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand
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Your doctor will probably decrease your dose gradually
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Trazodone may cause other side effects
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Doses often are adjusted slowly upwards to find the optimal dose
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Stop taking trazodone and call your doctor imm
ediately if you experience a prolonged (4 hours or longer), painful, or inappropriate erection
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Neither clinical studies nor epidemiological studies conducted to date, however, have shown an association between administration of these drugs and mammary tumorigenesis: Available evidence is considered too limited to be conclusive at this time
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Trazodone may enhance the response to alcohol and the effects of barbiturates and other CNS depressants and patients should be cautioned accordingly
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Trazodone is chemically unrelated to the serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the monoamine oxidase inhibitors (MAO inhibitors)
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Call your child's doctor right away if he or she experiences any of these symptoms: new or worsening depression; thinking about harming or killing him- or herself or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; frenzied abnormal excitement, or any other sudden or unusual changes in behavior
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This could lead to a serious condition requiring surgery
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It is rarely prescribed as monotherapy these days
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('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect
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o not stop taking trazodone without talking to your doctor
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This same type of interaction may occur when trazodone is used with selegiline (Eldepryl)
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It may take 2 weeks or longer before you feel the full benefit of trazodone
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Episodes of complex partial seizures have been reported in a small number of patients
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Food also increases the amount of drug absorbed into the body
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Drugs in the MAO-inhibitor class include isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate
), and procarbazine (Matulane)
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Hell, Desyrel is rarely prescribed at all, the generic trazodone is what is in all those bottles
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Dosing ranged from 225 to 450 mg/day for bupropion and 150 to 400 mg/day for trazodone
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Male patients with prolonged or inappropriate erections should immediately discontinue the drug and consult their physician
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Many experts believe that an imbalance among the different neurotransmitters is the cause of depression
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Weight measurements at the time of discontinuation indicated a 2
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Trazodone also may affect ejaculation, orgasm and libido
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Talk to your doctor about the possible risks of using this medication for your condition
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As with all antidepressants, it may take several weeks for the full effects of treatment to be seen
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Priapism (including clitoral priapism in women), a painful condition in which the penis (or clitoris) remains in an erect position, has been reported in patients receiving trazodone
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5-lb mean weight loss for the bupropion treatment group and a 1
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Tissue culture experiments indica
te that approximately 33% of human breast cancers are prolactin dependent in vitro, a factor of potential importance if the prescription of these drugs is contemplated in a patient with a previously detected breast cancer
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Trazodone also may increase directly the action of serotonin
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Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners
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One glass of grapefruit juice once in a while is not likely to have this effect on most people, but drinking large amounts, or drinking it regularly is proven to
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Trazodone is also sometimes used to treat schizophrenia (long lasting, disabling mental illness in which the patient loses touch with reality); anxiety (excessive worry); alcohol abuse; and abnormal, uncontrollable movements that may be experienced as side effects of other medications
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The major neurotransmitters are acetylcholine, norepinephrine, dopamine and serotonin
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Your child's doctor may also want to speak with you or your child by telephone from time to time
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If your child's doctor has prescribed trazodone for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment
and any time his or
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Talk to your doctor about the risk of taking trazodone
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If the condition persists for more than 24 hours, it would be advisable for the treating physician to consult a urologist or appropriate specialist in order to decide on a management approach
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Bupropion and trazodone were compared in a two-center, double-blind clinical trial of outpatients with moderate to severe major depression
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To help you remember to take trazodone, take it around the same times every day
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Be sure that your child keeps all appointments for office visits or telephone
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Call your doctor if you have any unusual problems while taking this medication
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Occurrence of drowsiness may require the administration of a major portion of the daily dose at bedtime or a reduction of dosage
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Drug information contained herein may be time sensitive
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Desyrel (trazodone) is the official antidepressant of Sleepy-bye Land
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Your doctor may decrease your dose once your condition is controlled
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Elderly pati
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The most commonly noted side effects associated with trazodone are nausea, dizziness, insomnia, agitation, tiredness, dry mouth, constipation, lightheadedness, headache, low blood pressure, blurred vision, and confusion
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Inhibition of this enzyme by various other substances may delay its degradation, leading to high blood levels of trazodone
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You may also require special monitoring during treatment if you have any type of heart disease, including a past heart attack, high blood pressure, irregular heartbeats, or chest pain (angina)
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If a patient is swit
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Although the exact mechanism of action of trazodone is unknown, it probably improves symptoms of depression by inhibiting the uptake of serotonin by nerves in the brain
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Trazodone controls depression, but does not cure it
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Such combinations may lead to confusion, high blood pressure and tremor
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During prolonged maintenance therapy the dosage should be kept at the lowest effective level
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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient
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Arrhythmias identified include isolated PVC's, ventricular couplets, and in 2 patients short episodes (3 to 4 beats) of ventricular tachycardia
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Trazodone is metabolised by CYP3A4, a liver enzyme (PMID 9616194)
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Trazodone may cause painful, long lasting erections in males
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At the end of treatment, 58% of the bupropion-treated patients and 4
6% of the trazodone-treated patients were considered much or very
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Increased serum digoxin and phenytoin levels have been reported to occur in patients receiving trazodone concurrently with either of those 2 drugs
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