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Do not take more or less of it, take it more often, or take it for a longer time than prescribed by your doctor [link widoczny dla zalogowanych] Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides [link widoczny dla zalogowanych] Drinking grapefruit juice is discouraged in patients taking trazodone [link widoczny dla zalogowanych] While trazodone is not a true member of the SSRI class of antidepressants, it does still share many properties of the SSRIs, especially the possibility of discontinuation syndrome if the medication is stopped too quickly [link widoczny dla zalogowanych] Anorexia and anxiety were reported significantly more often for the bupropion treatment group, whereas somnolence, appetite increase, and edema were reported signi
ficantly more often for the trazodone treatment group [link widoczny dla zalogowanych] Continue to take trazodone even if you feel well [link widoczny dla zalogowanych] Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand [link widoczny dla zalogowanych] Your doctor will probably decrease your dose gradually [link widoczny dla zalogowanych] Trazodone may cause other side effects [link widoczny dla zalogowanych] Doses often are adjusted slowly upwards to find the optimal dose [link widoczny dla zalogowanych] Stop taking trazodone and call your doctor imm
ediately if you experience a prolonged (4 hours or longer), painful, or inappropriate erection [link widoczny dla zalogowanych] Neither clinical studies nor epidemiological studies conducted to date, however, have shown an association between administration of these drugs and mammary tumorigenesis: Available evidence is considered too limited to be conclusive at this time [link widoczny dla zalogowanych] Trazodone may enhance the response to alcohol and the effects of barbiturates and other CNS depressants and patients should be cautioned accordingly [link widoczny dla zalogowanych] Trazodone is chemically unrelated to the serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the monoamine oxidase inhibitors (MAO inhibitors)
[link widoczny dla zalogowanych] Call your child's doctor right away if he or she experiences any of these symptoms: new or worsening depression; thinking about harming or killing him- or herself or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; frenzied abnormal excitement, or any other sudden or unusual changes in behavior [link widoczny dla zalogowanych] This could lead to a serious condition requiring surgery [link widoczny dla zalogowanych] It is rarely prescribed as monotherapy these days [link widoczny dla zalogowanych] ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect [link widoczny dla zalogowanych] D
o not stop taking trazodone without talking to your doctor [link widoczny dla zalogowanych] e [link widoczny dla zalogowanych] This same type of interaction may occur when trazodone is used with selegiline (Eldepryl) [link widoczny dla zalogowanych] It may take 2 weeks or longer before you feel the full benefit of trazodone [link widoczny dla zalogowanych] Episodes of complex partial seizures have been reported in a small number of patients [link widoczny dla zalogowanych] Food also increases the amount of drug absorbed into the body [link widoczny dla zalogowanych] Drugs in the MAO-inhibitor class include isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate
), and procarbazine (Matulane) [link widoczny dla zalogowanych] Hell, Desyrel is rarely prescribed at all, the generic trazodone is what is in all those bottles [link widoczny dla zalogowanych] Dosing ranged from 225 to 450 mg/day for bupropion and 150 to 400 mg/day for trazodone [link widoczny dla zalogowanych] Male patients with prolonged or inappropriate erections should immediately discontinue the drug and consult their physician [link widoczny dla zalogowanych] Many experts believe that an imbalance among the different neurotransmitters is the cause of depression [link widoczny dla zalogowanych] Weight measurements at the time of discontinuation indicated a 2
[link widoczny dla zalogowanych] Trazodone also may affect ejaculation, orgasm and libido [link widoczny dla zalogowanych] Talk to your doctor about the possible risks of using this medication for your condition [link widoczny dla zalogowanych] As with all antidepressants, it may take several weeks for the full effects of treatment to be seen [link widoczny dla zalogowanych] Priapism (including clitoral priapism in women), a painful condition in which the penis (or clitoris) remains in an erect position, has been reported in patients receiving trazodone [link widoczny dla zalogowanych] 5-lb mean weight loss for the bupropion treatment group and a 1 [link widoczny dla zalogowanych] Tissue culture experiments indica
te that approximately 33% of human breast cancers are prolactin dependent in vitro, a factor of potential importance if the prescription of these drugs is contemplated in a patient with a previously detected breast cancer [link widoczny dla zalogowanych] Trazodone also may increase directly the action of serotonin [link widoczny dla zalogowanych] Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners [link widoczny dla zalogowanych] One glass of grapefruit juice once in a while is not likely to have this effect on most people, but drinking large amounts, or drinking it regularly is proven to
[link widoczny dla zalogowanych] Trazodone is also sometimes used to treat schizophrenia (long lasting, disabling mental illness in which the patient loses touch with reality); anxiety (excessive worry); alcohol abuse; and abnormal, uncontrollable movements that may be experienced as side effects of other medications [link widoczny dla zalogowanych] The major neurotransmitters are acetylcholine, norepinephrine, dopamine and serotonin [link widoczny dla zalogowanych] Your child's doctor may also want to speak with you or your child by telephone from time to time [link widoczny dla zalogowanych] If your child's doctor has prescribed trazodone for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment
and any time his or
her dose is increased or decreased [link widoczny dla zalogowanych] Talk to your doctor about the risk of taking trazodone [link widoczny dla zalogowanych] If the condition persists for more than 24 hours, it would be advisable for the treating physician to consult a urologist or appropriate specialist in order to decide on a management approach [link widoczny dla zalogowanych] Bupropion and trazodone were compared in a two-center, double-blind clinical trial of outpatients with moderate to severe major depression [link widoczny dla zalogowanych] To help you remember to take trazodone, take it around the same times every day [link widoczny dla zalogowanych] Be sure that your child keeps all appointments for office visits or telephone
conversations with his or her doctor [link widoczny dla zalogowanych] Call your doctor if you have any unusual problems while taking this medication [link widoczny dla zalogowanych] Occurrence of drowsiness may require the administration of a major portion of the daily dose at bedtime or a reduction of dosage [link widoczny dla zalogowanych] Drug information contained herein may be time sensitive [link widoczny dla zalogowanych] Desyrel (trazodone) is the official antidepressant of Sleepy-bye Land [link widoczny dla zalogowanych] Your doctor may decrease your dose once your condition is controlled [link widoczny dla zalogowanych] Elderly pati
ents and debilitated persons may need lower doses [link widoczny dla zalogowanych] The most commonly noted side effects associated with trazodone are nausea, dizziness, insomnia, agitation, tiredness, dry mouth, constipation, lightheadedness, headache, low blood pressure, blurred vision, and confusion [link widoczny dla zalogowanych] Inhibition of this enzyme by various other substances may delay its degradation, leading to high blood levels of trazodone [link widoczny dla zalogowanych] You may also require special monitoring during treatment if you have any type of heart disease, including a past heart attack, high blood pressure, irregular heartbeats, or chest pain (angina) [link widoczny dla zalogowanych] If a patient is swit
ched from trazodone to an MAO inhibitor, at least one week should be allowed after stopping the trazodone before the MAO inhibitor is begun [link widoczny dla zalogowanych] Although the exact mechanism of action of trazodone is unknown, it probably improves symptoms of depression by inhibiting the uptake of serotonin by nerves in the brain [link widoczny dla zalogowanych] Trazodone controls depression, but does not cure it [link widoczny dla zalogowanych] Such combinations may lead to confusion, high blood pressure and tremor [link widoczny dla zalogowanych] During prolonged maintenance therapy the dosage should be kept at the lowest effective level
[link widoczny dla zalogowanych] The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient [link widoczny dla zalogowanych] Arrhythmias identified include isolated PVC's, ventricular couplets, and in 2 patients short episodes (3 to 4 beats) of ventricular tachycardia [link widoczny dla zalogowanych] Trazodone is metabolised by CYP3A4, a liver enzyme (PMID 9616194) [link widoczny dla zalogowanych] Trazodone may cause painful, long lasting erections in males [link widoczny dla zalogowanych] At the end of treatment, 58% of the bupropion-treated patients and 4
6% of the trazodone-treated patients were considered much or very
much improved [link widoczny dla zalogowanych] Increased serum digoxin and phenytoin levels have been reported to occur in patients receiving trazodone concurrently with either of those 2 drugs [link widoczny dla zalogowanych]